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<p>Contributors</p> <p>Preface</p> <p><b>I. General Considerations</b></p> <p>1. Tuberculosis in History: Did It Change the Way We Live? <br /> <i>Thomas M. Daniel</i></p> <p>2. Epidemiology and Host Factors <br /> <i>Jay B. Mehta and Asim K. Dutt</i></p> <p>3. Perspectives for Developing New Tuberculosis Vaccines Derived from the Pathogenesis of Tuberculosis <br /> <i>Arthur M. Dannenberg, Jr. and Bappaditya Dey</i></p> <p>4. Laboratory Diagnosis and Susceptibility Testing for Mycobacterium tuberculosis <br /> <i>Gary W. Procop</i></p> <p>5. Diagnosis of Latent Tuberculosis Infection<br /> <i>Alfred A. Lardizabal and Lee B. Reichman</i></p> <p>6. Treatment of Latent Tuberculosis Infection <br /> <i>Connie A. Haley</i></p> <p>7. Chemotherapy of Tuberculosis <br /> <i>Thomas E. Dobbs and Risa M. Webb</i></p> <p>8. The Role of Therapeutic Drug Monitoring in Mycobacterial Infections <br /> <i>Charles Peloquin</i></p> <p>9. Therapy of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis <br /> <i>Barbara J. Seaworth and David E. Griffith</i></p> <p>10. Role of Surgery in the Diagnosis and Management of Tuberculosis <br /> <i>Alan D.L. Sihoe</i></p> <p>11. Mycobacterium bovis BCG and New Vaccines for the Prevention of Tuberculosis <br /> <i>Timothy Lahey and C. Fordham Von Reyn</i></p> <p>12. Tuberculosis—a World Health Organization Perspective<br /> <i>Giovanni Sotgiu, Giorgia Sulis, and Alberto Matteelli</i></p> <p>13. Crisis-Affected Populations and Tuberculosis <br /> <i>Dominik Zenner</i></p> <p>14. Tuberculosis in Enclosed Populations<br /> Sorana Segal-Maurer</p> <p>15. Role of the Health Department in Tuberculosis Prevention and Control—Legal and Public Health Considerations<br /> <i>Carla Jeffries, Phil LoBue, Terence Chorba, Beverly Metchock, and Ijaz Kashef</i></p> <p><b>II. Clinical Syndromes</b></p> <p>16. Pulmonary Tuberculosis <br /> <i>Sarah M. Lyon and Milton D. Rossman</i></p> <p>17. Upper Respiratory Tract Tuberculosis <br /> <i>Surinder K. Jindal, Aditya Jindal, and Ritesh Agarwal</i></p> <p>18. Tuberculous Otomastoiditis <br /> <i>Jonathan M. Hand and George A. Pankey</i></p> <p>19. Ocular Tuberculosis <br /> <i>Daniel M. Albert and Meisha L. Raven</i></p> <p>20. Central Nervous System Tuberculosis <br /> <i>John M. Leonard</i></p> <p>21. Tuberculous Lymphadenitis and Parotitis <br /> <i>Juan Carlos Cataño and Jaime Robledo</i></p> <p>22. Urogenital Tuberculosis <br /> <i>André A. Figueiredo, Antônio M. Lucon, and Miguel Srougi</i></p> <p>23. Musculoskeletal Tuberculosis <br /> <i>Henry M. Blumberg and Michael K. Leonard, Jr.</i></p> <p>24. Cardiovascular Tuberculosis <br /> <i>John A. Crocco</i></p> <p>25. Gastrointestinal Tuberculosis <br /> <i>Eric H. Choi and Walter J. Coyle</i></p> <p>26. Tuberculous Peritonitis <br /> <i>Urvashi Vaid and Gregory C. Kane</i></p> <p>27. Tuberculosis of the Liver, Biliary Tract, and Pancreas <br /> <i>G. Shelton McMullan and James H. Lewis</i></p> <p>28. Cutaneous Tuberculosis <br /> <i>Michael K. Hill and Charles V. Sanders</i></p> <p>29. Miliary Tuberculosis <br /> <i>Surendra K. Sharma and Alladi Mohan</i></p> <p>30. Endocrine and Metabolic Aspects of Tuberculosis <br /> <i>Christopher Vinnard and Emily A. Blumberg</i></p> <p>31. Hematologic Complications of Tuberculosis <br /> <i>Shyam S. Balepur and David Schlossberg</i></p> <p>32. Tuberculosis in Infants and Children <br /> <i>Jeffrey R. Starke and Gabriella S. Lamb</i></p> <p>33. Tuberculosis and Pregnancy—Maternal, Fetal, and Neonatal Considerations <br /> <i>Jane M. Gould and Stephen C. Aronoff</i></p> <p>34. Tuberculosis Associated with HIV Infection <br /> <i>Kelly E. Dooley and Jeffrey A. Tornheim</i></p> <p>35. Diabetes and Tuberculosis <br /> <i>Blanca I. Restrepo</i></p> <p>36. Tuberculosis and Transplantation <br /> <i>José M. Aguado, José Tiago Silva, Palash Samanta, and Nina Singh</i></p> <p>37. Biologic Agents and Tuberculosis <br /> <i>Claudia C. Dobler</i></p> <p>38. Paradoxical Reactions and the Immune Reconstitution Inflammatory Syndrome <br /> <i>L.W. Preston Church, Amit Chopra, and Marc A. Judson</i></p> <p><b>III. Nontuberculous Mycobacteria</b></p> <p>39. Nontuberculous Mycobacteria—Overview <br /> <i>Won-Jung Koh</i></p> <p>40. Mycobacterium avium Complex Disease <br /> <i>Charles L. Daley</i></p> <p>41. Rapidly Growing Mycobacteria <br /> <i>Barbara A. Brown-Elliott and Julie V. Philley</i></p> <p>42. Mycobacterium kansasii <br /> <i>James C. Johnston, Leslie Chiang, and Kevin Elwood</i></p> <p>43. Mycobacterium marinum <br /> <i>Alexandra Aubry, Faiza Mougari, Florence Reibel, and Emmanuelle Cambau</i></p> <p>44. Mycobacterium bovis and Other Uncommon Members of the Mycobacterium tuberculosis Complex <br /> <i>Jaime Esteban and Maria-Carmen Muñoz-Egea</i></p> <p>45. Other Slow-Growing Nontuberculous Mycobacteria <br /> <i>Marvin J. Bittner and Laurel C. Preheim</i></p> <p>Index</p>

<p><b>David Schlossberg, MD, FACP,</b> is Medical Director of the Tuberculosis Control Program at the Philadelphia Department of Public Health. He is Professor of Medicine at the Lewis Katz School of Medicine at Temple University and Adjunct Professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania. He is a graduate of Yale University and Tufts Medical School and completed his medical residency at Mount Sinai Hospital, New York, and his infectious disease fellowship at Emory University, Atlanta. Dr. Schlossberg has received numerous teaching awards and has published more than 100 articles, editorials, and book chapters and 28 books on infectious disease.

<p><b>TUBERCULOSIS</b></p> <p>AND NONTUBERCULOUS MYCOBACTERIAL INFECTIONS <p><b>SEVENTH EDITION</b> <p><b>Complete coverage of every aspect of tuberculosis and related mycobacterial infections</b> <p>“Tuberculosis appears to be as old as humanity itself.” Despite many advancements since the 1882 identification of <i>Mycobacterium tuberculosis</i> as the causative agent of tuberculosis, it remains one of the top 10 causes of death worldwide and threatens the effectiveness of our therapeutic arsenal. In 2015, 1.8 million people died of tuberculosis and almost half a million new cases of multidrug-resistant tuberculosis were diagnosed. <p>For <i>Tuberculosis and Nontuberculous Mycobacterial Infections,</i> Dr. Schlossberg assembled an international team of experts to write about nearly every facet of the prevention, diagnosis, and treatment of tuberculosis and nontuberculous mycobacterial infections. In addition to presenting the latest clinical data, epidemiological findings, and policy and strategy recommendations of the World Health Organization, four new chapters cover topics of critical importance: <ul><li>The role of therapeutic drug monitoring in mycobacterial infections</li> <li>The public health issues of refugees and migrants, and their exposure and transmission of tuberculosis resulting from humanitarian crises</li> <li>Diabetes mellitus as a significant risk factor for tuberculosis</li> <li>The increased risk of tuberculosis reactivation in people taking tumor necrosis factor alpha inhibitors and other biopharmaceuticals</li></ul> <p>Other chapters provide detailed information on the clinical, public health, and policy aspects of tracking and treating tuberculosis, including: <ul><li>The many presentations of tuberculosis, from pulmonary to ocular and cardiovascular to urogenital</li> <li>The complications that tuberculosis and antituberculosis therapy cause to the hematologic and endocrine systems</li> <li>Tuberculosis during pregnancy and in infants and children</li> <li>Treatment of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis</li> <li>Development of new vaccines</li> <li>Nontuberculous infections caused by mycobacteria found throughout our environment</li></ul> <p>The seventh edition of <i>Tuberculosis and Nontuberculous Mycobacterial Infections</i> is an essential resource for anyone working to prevent and treat tuberculosis and associated infections, from infectious disease specialists and pulmonologists to scientists, policymakers, and epidemiologists. <p><i>A truly modern book that offers students, practitioners, and all readers the chance for a full immersion into the science of tuberculosis.”</i> <p><b>—M<small>ARIO</small> R<small>AVIGLIONE</small>, MD,</b> Global TB Programme, World Health Organization <p>“<i>It’s difficult to improve on an already excellent book but Dr. Schlossberg and colleagues have done it again!”</i> <p><b>—B<small>URKE</small> A. C<small>UNHA</small>, MD, MACP,</b> Infectious Disease Division, Winthrop-University Hospital <p>“<i>This comprehensive book remains the most popular reference among physicians treating tuberculosis.”</i> <p><b>—L<small>EONID</small> H<small>EIFETS</small>, MD,</b> National Jewish Hospital (from a previous edition) <p>“<i>This book meets a demand for timely information…constitutes a ready and useful reference for general internists and primary care physicians.”</i> <p><b>—A<small>NNALS OF</small> I<small>NTERNAL</small> M<small>EDICINE</small> </b>(from a previous edition)

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